简单介绍

邹滔滔,博士,教授,博士生导师。20187月通过中山大学百人计划中青年杰出人才引进,全职到药学院工作。研究集中在化学、生物学、药学和医学的多学科交叉领域,主要包括金属药物化学、药物化学生物学、小分子生物探针等。曾获得SciFinder Future LeadersFinalist of Reaxys PhD PrizeSpringer Theses Prize、李嘉诚奖、香港青年科学家奖等国际和地区奖项。

ORCID IDhttps://orcid.org/0000-0001-9129-4398

Researcher ID: G-2044-2018

教育经历

2010.09-2015.02 香港大学化学系,导师:支志明院士,博士

2006.09-2010.06 武汉大学化学学院,导师:杨楚罗教授,本科

工作经历

2018.07-至今  中山大学药学院 教授

2018.03-2018.07  香港中文大学(深圳) 助理教授

2015.02-2018.02  斯科利普斯研究所(导师:Xiang-Lei Yang教授)、香港大学(导师:支志明教授)、华威大学(导师Peter J Sadler教授) 博士后

论著专利

代表性论文

  1. Zou, T.; Lum, C. T.; Lok, C.-N.; Zhang, J.-J.; Che, C.-M., Chemical biology of anticancer gold(III) and gold(I) complexes. Chem. Soc. Rev. 201544, 8786-8801 (Front Cover, ESI highly cited paper).

  2. Zou, T.; Lum, C. T.; Chui, S. S.-Y.; Che, C.-M., Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands: Thiol “Switch-on” Fluorescent Probes and Anti-Cancer Agents. Angew. Chem. Int. Ed. 201352, 2930-2933. (VIP)

  3. Zou, T.; Lum, C. T.; Lok, C.-N.; To, W.-P.; Low, K.-H.; Che, C.-M., A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo. Angew. Chem. Int. Ed. 201453, 5810-5814.

  4. Fung, S. K.;# Zou, T.;# Cao, B.; Lee, P.-Y.; Fung, Y. M. E.; Hu, D.; Lok, C.-N.; Che, C.-M., Cyclometallated Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands Engage Multiple Anti-Cancer Molecular Targets, Angew. Chem. Int. Ed. 201756, 3892-3896. (VIP)

  5. Zou, T.;# Liu, J.;# Lum, C. T.; Ma, C.; Chan, R. C.-T.; Lok, C.-N.; Kwok, W.-M.; Che, C.-M., Luminescent Cyclometalated Platinum(II) Complex Forms Emissive Intercalating Adducts with Double Stranded DNA and RNA: Differential Emissions and Anticancer Activities. Angew. Chem. Int. Ed. 2014, 53, 10119-10123.

  6. Fung, S. K.;# Zou, T.;# Cao, B.; Chen, T.; To, W.-P.; Yang, C.; Lok, C.-N.; Che, C.-M., Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA, Nat. Commun. 20167, 10655.

  7. Lok, C.-N.;# Zou, T.;# Zhang, J.-J.; Lin, I. W.-S.; Che, C.-M., Controlled-Release Systems for Metal-Based Nanomedicine: Encapsulated/Self-Assembled Nanoparticles of Anticancer Gold(III)/Platinum(II) Complexes and Antimicrobial Silver Nanoparticles. Adv. Mater. 201426, 5550-5557.

  8. Zou, T.;# Lok, C.-N.,# Wan, P.-K., Zhang, Z.-F., Fung, S.-K., Che, C.-M. Anticancer Metal N-Heterocyclic carbene complexes of gold, platinum and palladium, Curr. Opin. Chem. Biol.201843, 30-36.

(#equal contribution)

其他

欢迎具有化学、药学或生物学背景的同学申请或报考本课题组研究生或博士生,同时拟招聘多名博士后和特聘研究员,课题组将提供丰厚待遇。