简单介绍

郭磊 博士、副教授、硕士生导师。2017年1月通过中山大学“百人计划”引进入职药学院,现为罗海彬教授团队组成员。曾在JACS, Angew. Chem. Int. Ed., Adv. Mater. 等期刊发表论文多篇。

教育经历

2001.09 – 2005.07  中国药科大学,制药工程,学士

2005.09 – 2008.07  中国药科大学,药物化学,硕士(导师 黄文龙)

2006.10 – 2008.06  中科院上海有机化学研究所,生命有机国家重点实验室,联合培养(导师 马大为)

2009.09 – 2013.02  香港浸会大学,有机化学,博士(导师 黄文成)

工作经历

2008.07 – 2009.08  中科院上海有机化学研究所,研究助理

2013.03 – 2016.12  香港浸会大学,博士后

2017.01 – 至今       中山大学药学院,副教授,药物化学

科研项目

国自然青年科学基金项目:肿瘤细胞靶向、核仁RNA结构选择性染色的红色吲哚半花菁类探针分子:设计、合成和作用机制研究(2018.01-2020.12)

论著专利

(1) Lei Guo, Siu Wai Tsang, Tong-Xin Zhang, Kang-Lun Liu, Yi-Fu Guan, Bo Wang, Han-Dong Sun, Hong-Jie Zhang, Man Shing Wong, Efficient Semisynthesis of (−)-Pseudoirroratin A from (−)-Flexicaulin A and Assessment of Their Antitumor Activities, ACS Med. Chem. Lett. 2017, 8(3), 372−376.

 

(2) Lei Guo, King Fai Li, Xiaoqin Zhang, Kok Wai Cheah, Man Shing Wong, Highly Efficient Multiphoton-Pumped Frequency-Upconversion Stimulated Blue Emission with Ultralow Threshold from Highly Extended Ladder-Type Oligo(p-phenylene)s, Angew. Chem. Int. Ed., 2016, 55(36): 10639-10644.

 

(3) Lei Guo, Miu Shan Chan, Di Xu, Dick Yan Tam, Frédéric Bolze, Pik Kwan Lo, Man Shing Wong, Indole-based Cyanine as a Nuclear RNA-Selective Two-Photon Fluorescent Probe for Live Cell Imaging, ACS Chem. Biol., 2015, 10(5):1171-1175.

 

(4) Lei. Guo, Man Shing Wong, Multiphoton Excited Fluorescent Materials for Frequency Upconversion Emission and Fluorescent Probes, Adv. Mater., 2014, 26(31): 5400-5428.

 

(5) Lei Guo, King Fai Li, Man Shing Wong, Kok Wai Cheah, Star-shaped ladder-type ter(p-phenylene)s for efficient multiphoton absorption, Chem. Commun., 2013, 49(34): 3597-3599.

 

(6) Hai Hua Fan#, Lei Guo#, King Fai Li, Man Shing Wong, Kok Wai Cheah, Exceptionally Strong Multiphoton-Excited Blue Photoluminescence and Lasing from Ladder-Type Oligo(p-phenylene)s, J. Am. Chem. Soc., 2012, 134(17): 7297-7300. (共同一作)

 

(7) Lei Guo, Ben Li, Wenlong Huang, Gang Pei, Dawei Ma, Elaboration of the Oxazepine Ring System via CuI/L-Proline-Catalyzed Intramolecular Aryl Amination, Synlett, 2008, 12: 1833-1836.

 

[1] 黄文成,张卫锋,郭磊,用于太阳能电池应用的低带隙的二氰基乙烯基和三氰基乙烯基低聚噻吩,2015,中国,CN103524481 B.

 

[2] Man Shing Wong, Weifeng Zhang, Lei Guo, Low bandgap dicyanovinyl and tricyanovinyl oligothiophenes for solar cell applications, 2015, USA US8975419 B2.

 

[3] Lei Guo, Di Xu, See-Lok Ho, Chung-Yan Poon, Olivia T. W. Hung Wing Li, Ken K. L. Yung, Daniel W. J. Kwong, Ricky M. S. Wong, Imaging beta-Amyloid Peptides and Inhibition of beta-Amyloid Peptide Aggregation, 2016, US 9,255,933 B2.